Better outcome of vascular accesses for hemodialysis patients

Renal failure requires chronic hemodialisis treatment with extracorporeal blood circulation. This in turn requires the execution of arm vessel surgery known as arteriovenous fistula. Currently these procedures are done relying almost exclusively on the surgeon experience. Even with skilled surgeons, however, a high percentage of patients experience complications that require reoperation.

The ARCH system makes possible to plan such surgery in advance on the basis of patient’s data, and obtain a prediction of the vascular access function outcome, allowing an optimisation of the surgical procedure and a reduction of associated complications such as non-maturation.

A prospective study is running coordinated by the Mario Negri Institue in Italy. Preliminary results on 63 patients confirm the efficacy of this technology. 

Bode A, Caroli A, Huberts W, Planken N, Antiga L, Bosboom M, Remuzzi A, Tordoir J. Clinical study protocol for the ARCH project - computational modeling for improvement of outcome after vascular access creation. J Vasc Access. 2011 Oct-Dec;12(4):369-76. doi: 10.5301/JVA.2011.8382.
Caroli A, Manini S, Antiga L, Passera K, Ene-Iordache B, Rota S, Remuzzi G, Bode A, Leermakers J, van de Vosse FN, Vanholder R, Malovrh M, Tordoir J, Remuzzi A. Validation of a patient-specific hemodynamic computational model for surgical planning of vascular access in hemodialysis patients. Kidney Int. 2013 Dec;84(6):1237-45. doi: 10.1038/ki.2013.188.
Public dissemination: Euronews coverage target also ARCH project www.euronews.com/2012/02/14/picture-my-body/

Avicenna Alliance news

In silico method mentioned in JRC report on alternatives to animal testing

On 7 February, the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) - which is an...

find out more ›

Artificial Intelligence and clinical research: which issues remain?

This issue is discussed in the new article written under the direction of Vincent Diebolt, Director of the French Clinical Research...

find out more ›

FEops  joins Avicenna Alliance

As further evidence of the Alliance’s growing momentum, Avicenna Alliance is happy to announce the newest addition to our list of members: FEops.

find out more ›

Show all activites