Lieve Wierinck, Member of the European Parliament

European Parliament

Lieve Wierinck is a Flemish politician for the liberal Open VLD party. Mrs. Wierinck holds a pharmaceutical degree from the VUB (Vrije Universiteit Brussel). In addition, she obtained a Post-graduate degree of Pharmaceutical management in 2006 at the University of Hasselt. In line with her academic background, she owned and managed a pharmacy for nearly 30 years.

Before joining the European Parliament, Lieve was leader of the party fraction in Zaventem, followed by her twelve-year presidency of the OCMW (Public Centre for Social Welfare), where she managed a staff of 150 people. She combined this with her obligations as a fulltime member of the City Council of Zaventem. From December 2011 until June 2014, she was a member of the Belgian Federal Parliament, where she was a member of the Committee for Public Health, Environment and Social Renewal, and of the Advisory Committee on Societal Emancipation.

In May 2016, Lieve replaced Mr. Philippe De Backer as a Member of the European Parliament, where she is a full member of the Industry, Technology, Research and Energy Committee (ITRE) and a substitute Member of the Committee on Economic and Monetary affairs (ECON). Lieve also works on topics surrounding healthcare, as she strives for a progressive and affordable healthcare in Europe.

Ingrid Klingmann, MD, PhD, FFPM, FBCPM

European Forum for Good Clinical Practice (EFGCP), PHARMAPLEX bvba

Physician, specialized in General Medicine, Clinical Pharmacology and Pharmaceutical Medicine with over 30 years of experience in different senior medical, operational and managerial functions in pharmaceutical industry, CROs and clinical trial sites with focus on clinical trial design and management, ethical and regulatory aspects.

Since January 2003 she has her own pharmaceutical development and site management support consulting company.

Dr. Klingmann is Chairman of the Board of the European Forum for Good Clinical Practice (EFGCP). On behalf of EFGCP she was and is involved in different FP7- and IMI-funded projects (ICREL, PatientPartner, PharmaTrain, EUPATI, Combacte-Magnet) and with her company in the FP7-funded paediatric LENA project and the IMI-project SPRINTT. Her broad professional background as physician with experience in patient care, clinical development, site management and patient engagement enables Dr. Klingmann to bridge the gaps between the interests and skills of all different stakeholders in medicines development with the aim to develop new patient-relevant treatments more efficiently.

Dr. Klingmann is also President of PharmaTrain Federation and teaches different medicine development topics in diploma and master courses at the University of Bonn, Germany, University of Basel, Switzerland, and the Université Libre de Bruxelles, Belgium.

Adriano Henney, PhD

Chairman of the Board of the Avicenna Alliance

Dr Henney has a PhD in Medicine with research interests cardiovascular disease at the pathological, cellular, molecular and genetic level. After an academic career in laboratories in London, Cambridge and Oxford, he moved into industry, spending 13 years with AstraZeneca.

Ultimately leading global programmes exploring strategic improvements aimed at reducing drug failure in development, he created and headed a new department that focused on pathway mapping and modelling, which evolved to establish the practice of Systems Biology, supporting projects in discovery and development. Dr Henney has extensive experience in directing and managing large, complex teams across disciplinary, cultural and geographic boundaries, latterly in the area of Systems Biology and Systems Medicine. His experience in this area led to an invitation to direct the major €50M German national flagship programme, The Virtual Liver Network, at the time the largest Systems Biology programme in Europe, involving the management of over 200 contributing scientists from a range of disciplines, including clinicians, in 36 independent institutions, including industry, located across Germany.

Following the end of the VLN Programme, Dr Henney was elected to be part-time Executive Director of the Virtual Physiological Human Institute, a not-for-profit organisation promoting the use of computational modelling and simulation to interpret quantitative biological information and understand the dynamics of biological and physiological function. As part of that role, he was responsible for establishing a new partnership with industry, the Avicenna Alliance for Predictive Medicine.

Michael R.S. Hill, PhD, MBA

Vice President Corporate Science, Technology and Clinical Affairs, Medtronic

Michael Hill joined Medtronic in July 1992 as a Scientist in the Cardiac Rhythm Management division of Medtronic in Minneapolis, MN.  He has served in research, clinical, program, international and management roles over his tenure at Medtronic.  He is a Technical Fellow (1998) and Bakken Fellow (2001).  He was awarded a CRDM Star of Excellence award in 2011.  In 2012, he was inducted as Fellow of the American Institute of Medical and Biological Engineering.  In 2013, he was awarded the Distinguished Engineering Alumni award from Duke University.  He was awarded the Medtronic Patent of Distinction Award in 2014.  He currently leads the global Corporate Science, Technology and Clinical Affairs organization.  He holds over 60 patents, has authored several manuscripts and abstracts, and often is an invited lecturer at international cardiac-related conferences and university events. 

A native of Jackson, Tennessee, Dr. Hill received his BSE [Biomedical and Electrical Engineering] and BS [Mathematics] Degrees from Duke University, MS and PhD [Biomedical Engineering] Degrees from Case Western Reserve University, and MBA [Management] Degree from the University of St. Thomas.

Geena Malhotra

Global Head of Integrated Product Development, Cipla

Geena Malhotra is the Global President of Integrated Research & Development and also is a part of Management Council of Cipla Ltd the leading pharmaceutical company in India, with an annual turnover of over $2 billion in sales. Cipla is the third largest company in India, with anti-HIV and respiratory as its main forte. Cipla has over 70 % market share in Respiratory space in India and is a formidable force to reckon with.

Geena Malhotra completed her bachelor’s degree in pharmacy in 1985 in Mumbai and an pursued Executive MBA from Washington University, St. Louis in 2017.

Geena has been the pillar of research and development for Cipla for over 3 decades, a company that started as an API manufacturer and diversified to over 40 dosage forms, enabled singularly by Geena’s leadership over the last three decades, touching almost every product and device that Cipla has in the market today. She has changed the trajectory of the company by introducing and delivering complex generics based on technology of nano particles, liposomes and the world’s first-in-class range of respiratory products and drug device combinations, all in the environment of Quality by Design. Geena is a technologist at heart, and her passion has led her to develop not just pharmaceuticals but even the machines behind it. She has been instrumental in bringing the science of efficient drug delivery systems such as drug device combinations for respiratory therapeutics, targeted drug delivery using simulation tools etc. at Cipla.  She has to her credit 300 patents filed in the areas of formulation development and technology in solid oral dosage forms, topical delivery systems and inhalation medical devices. She is responsible for providing technical leadership to multi-disciplinary R&D teams as well as operate within a cross functional environment to build and deliver a high throughput R&D with technology being the core focus. To her credit she has been constantly reinventing and repurposing to keep the momentum of research of  her teams to adopt computational sciences  and simulations to improve the quality and speed of development, keeping the needs of patients above all and fulfill the purpose of “caring for Life”.

Thierry Marchal

Secretary General of the Avicenna Alliance, ANSYS Global Industry Director

As the ANSYS Global Industry Director since 2006, Thierry Marchal leads the medical devices, pharmaceutical and biotech strategy of ANSYS through the in silico and personalized medicine evolution by closely interacting with industrial innovators and SMEs, academic leaders and governmental and regulatory authorities such as the FDA and the EMA. In his 25+ years of professional experience, Thierry has worked as the Global Materials Market Segment Manager with Fluent and Product Manager for Polyflow. Thierry holds a degree in Mechanical Engineering from UCL. 

Tina Morrison, PhD

Deputy Director, Division of Applied Mechanics and Chair of FDA's Modeling and Simulation Working Group

Dr. Morrison is the Chair of the new FDA-wide working group on Modeling and Simulation, sponsored by the Office of the Chief Scientist, which launched in the Fall of 2016. She has been serving as the Regulatory Advisor of Computational Modeling for the Office of Device Evaluation since 2011. In that capacity, she leads the Regulatory Review of Computational Modeling working group at CDRH, which has developed guidance documents on the use of modeling and simulation in the regulatory evaluation of medical devices. She dedicates much of her energy towards advancing regulatory science through modeling and simulation because she believes the future of medical product design and evaluation, and thus enhanced patient care, lies with computation and enhanced visualization.

She serves as Chair of the ASME Committee on Verification and Validation of Computational Modeling, as well as the subcommittee (V&V40) on Computational Modeling of Medical Devices, where she is leading the development of a strategy to assess the credibility of computational models. She is working with a team at CDRH to implement this strategy into the review of premarket submissions that leverage computational modeling. For seven years, she was a scientific reviewer on a variety of medical device premarket submissions in Cardiovascular Devices.

Dr. Morrison is a mechanical engineer who studied Cardiovascular Biomechanics as a post-doctoral fellow at Stanford University. During that time, she investigated the in vivo biomechanics of the aorta using gated CT imaging; those data are now used as boundary condition inputs for computational modeling and bench-testing of endovascular devices in premarket submissions. She received her PhD in Theoretical and Applied Mechanics from Cornell University in 2006.

Avicenna Alliance news

Welcome to our new member MDsim!

We are delighted to welcome our new member MDsim!

MDsim is a health-tech start-up, based in Luxembourg, active in the In-Silico Medicine. 

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Mapping the use of computational modelling and simulation in clinics: A survey

Computational modelling and simulation (CM&S) can be used in medicine to mimic biological processes with the goal of...

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Nathalie Virag is the new Avicenna International Affairs Working Group Leader!

Nathalie Virag, Ph.D is a Distinguished Scientist at Medtronic Corporate Technology & Innovation. She has more than 25...

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Second release of Avicenna Glossary now available!

This Glossary is a second release with an extended list of definitions; more concepts will be defined and existing definitions may be adjusted in...

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We are delighted to welcome France Biotech as a new Avicenna Partner

Founded in 1997, France Biotech is an independent association, uniting the country’s leading innovative health companies and their...

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The potential of in silico approaches to streamline drug development

This position paper highlights the potential of in silico medicine, using computational modelling and simulation to aid drug...

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We will give the entire healthcare community an exhaustive update on recent progress and achievements related to the adoption and deployment of in silico method...

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Avicenna Alliance Observer at IMDRF meeting in Brussels

The Avicenna Alliance had received the honor to be invited as an Observer to the International Medical Device Regulators Forum (IMDRF) meeting...

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Avicenna Alliance meets with MEPs in Strasbourg

During the European Parliament’s plenary session that took place in the second week of March, Avicenna had the unique opportunity to visit the European...

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Welcome RBF Morph!

Welcome to our new member RBF Morph! Based in Monte Compatri, Rome, RBF is a pioneer and leader in mesh morphing, a key technology used in engineering simulation.

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Mimesis is a new Avicenna member!

We are truly delighted to welcome Mimesis as a new Avicenna member!

Mimesis is an innovative start-up, founded in 2020 as a spinoff of the University of Catania,...

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Shiny Martis is the new Pharmaceutical Strategy TF Co-Chair

We are delighted to welcome Shiny Martis as the new Pharmaceutical Strategy TF Co-Chair.

Shiny is Academic Partnership and Customer...

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Numalogics is a new Avicenna member

We are honored to welcome Numalogics as a new Avicenna’s member!
Numalogics is a Montréal-based privately held company priding itself on its world-class...

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Congratulations to our new Working Group Leaders!

We are delighted to welcome Cécile Rousseau and Martha De Cunha who have been elected as new Working Group Leaders of the Avicenna's 

In Silico... find out more ›

In Silico Application (ISA) Working Group

Digital evidence can and must be used for regulatory approval in all parts of the world. The Research & Technology Working Group has made huge progress,...

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Working Group Leaders elections

Our warmest congratulations to Liesbet Geris and Mark Palmer for their reappointment as Working Group Leaders of the Avicenna's Research & Technology Working Group and...

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We are delighted to welcome NumeriCor as a new Avicenna member!

NumeriCor is a leading cardiac electrophysiology and mechanics modelling company providing end-to-end simulation control. 

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Avicenna Alliance Glossary of Terms for Computer Modeling and Simulation

There are occasional confusions and diverging opinions possibly leading to misunderstanding in the use of some In Silico...

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A range of authors across academia and industry, representing both the Avicenna Alliance and the Virtual Physiological Human Institute,...

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Toward a regulatory pathway for Using in Silico Trials in CE Marking of Medical Devices


A team of researchers of the In Silico World project, including several key Avicenna Alliance members, led...

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Avicenna Alliance response to the ICHE11A Consultation

The Avicenna Alliance strongly supports and welcomes the ICH’s proposed goal of harmonizing methods and strategies for improved paediatric drug...

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Avicenna Alliance Feedback to the European Health Data Space Call for Feedback

The Avicenna Alliance welcomes the proposal for the EHDS. The Alliance is a multistakeholder group with the mission of...

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We are honored to welcome Zimmer Biomet as a new Avicenna’s member!

Zimmer Biomet is a global medical technology leader with a comprehensive portfolio designed to maximize mobility and improve...

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Avicenna Alliance Response to 2023 Stakeholders' Targeted Consultation on EU4Health

The Avicenna Alliance stressed the need for further support and guidance for digital evidence from in silico...

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New Avicenna APAC Task Force

A new Task Force joined the International Affairs Working Group!

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Cécile De Coster is the new Avicenna Pharmaceutical Strategy Task Force Co-chair

We are proud to welcome Cécile De Coster as the new Avicenna Pharmaceutical Strategy Task Force co-chair!

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Avicenna Alliance goes on growing by welcoming Edwards Lifesciences as a new member!

Edwards Lifesciences is the global leader of patient-focused innovations for structural heart disease and...

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Avicenna Alliance is honoured to welcome Alfasigma as a new member!

Privately owned, Alfasigma is one of the leading Italian pharmaceutical companies, present in over 90 countries, through...

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EU-funded project successfully develops AI software that grows and treats cancerous tumors 

The Horizon Europe 2020 project EVO-NANO (Evolvable platform for programmable nanoparticle-based cancer...

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In silico used to validate Omicron variant detection method! 

The Joint Research Centre (JRC) has developed a new method to detect the Omicron variant of COVID-19, which differs in its nucleic acid...

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The priorities of the upcoming French Presidency of the Council of the European Union - what’s new for Avicenna? 

The French Presidency of the Council of the European Union is due to start on 1...

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New Avicenna UK Insilico Regulatory Innovation Task Force

The Avicenna International Affairs Working Group adds a new task force to its structure.

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In Silico in Innovation – again!

The European Innovation Council (EIC) has released its second wave of “start-up champions” to receive funding for innovations through the EIC Accelerator. The EIC...

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Avicenna Alliance meets with MEPs to discuss in silico medicine

On 7 October, Dr. Liesbet Geris (Research Professor in Biomechanics and Computational Tissue Engineering at the Universities of Liège &...

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The Joint Research Centre advocates for a “paradigm change” to in silico research methods!

For the second week in a row, the Joint Research Centre (JRC) – part of the European Commission’s EU Science...

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The European Commission Joint Research Centre publishes a public knowledge base of non-animal models used in immuno-oncology

The Joint Research Centre (JRC), which is part of the European...

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The State of the (European) Union

On 15 September, Commission President Ursula von der Leyen delivered her second State of the Union speech at the European Parliament in Strasbourg. She took stock of...

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The BECA Beat 

The European Parliament’s Special Committee on Beating Cancer (BECA) met for the first time in September of 2020. BECA was established to create actionable recommendations for Member...

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Avicenna Alliance prepares for the next EU policy session 

As September begins, politicians have returned to their EU posts and are preparing for what will be a busy few months for health policy. The...

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Joint Research Centre of the Commission launches report on national strategies for Artificial Intelligence!

The Joint Research Centre of the European Commission (JRC) recently published a new report...

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Conference of the Slovenian Council Presidency addresses digital twin technologies and digitalisation in healthcare!

On 15 and 16 July, the Slovenian Presidency of the Council of the European Union ...

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WHO issues first global report on use of AI in healthcare

Artificial Intelligence (AI) applications in health innovation are rapidly increasing, reflecting the potential of these technologies to...

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Slovenian Presidency of the Council of the EU launches its six-month programme!

On 1 July, for the second time since joining the EU in 2004, Slovenia has taken over the Presidency of the Council of...

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Members of the European Parliament call EU Health Commissioner to place in silico medicine on her policy agenda from 2021 onwards!

On 22 June, a group of five Members of the European Parliament...

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Our new position paper on in silico evidence in the regulatory approval of medical devices is out!

The Avicenna Alliance is proud to announce the recent publication of its new position paper...

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Happy 5th Anniversary to the Avicenna Alliance!  

5 years ago, based on the very enlightening Avicenna Roadmap Project Report, the Avicenna Alliance was established at the suggestion of European...

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EU New Medical Device Regulation now in force! In silico mentioned for the first time

After a one-year postponement following the COVID-19 pandemic, the European Commission’s Medical Devices...

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The European Commission adopts Communication on Europe's global approach to cooperation in research and innovation

On 18 May, the European Commission adopted a Communication on its global approach...

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Avicenna Alliance provides feedback on the European Commissions’ roadmap for the revision of the EU general pharmaceuticals legislation

On 27 April, the Avicenna Alliance has submitted its feedback...

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